{"id":66218,"date":"2024-05-09T09:26:42","date_gmt":"2024-05-09T09:26:42","guid":{"rendered":"https:\/\/www.maryatech.com\/?p=66218"},"modified":"2024-05-09T09:50:37","modified_gmt":"2024-05-09T09:50:37","slug":"como-deben-mantenerse-las-salas-blancas","status":"publish","type":"post","link":"https:\/\/www.maryatech.com\/es\/how-should-clean-rooms-be-maintained\/","title":{"rendered":"\u00bfC\u00f3mo deben mantenerse los cuartos limpios?"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"66218\" class=\"elementor elementor-66218\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d3c0d57 e-flex e-con-boxed e-con e-parent\" data-id=\"d3c0d57\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3f3e0cf elementor-widget elementor-widget-heading\" data-id=\"3f3e0cf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u00bfC\u00f3mo deben mantenerse las salas limpias para evitar que disminuya la limpieza del aire?<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-de744de elementor-widget elementor-widget-text-editor\" data-id=\"de744de\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Durante el proceso de producci\u00f3n de medicamentos, es necesario evitar la contaminaci\u00f3n por part\u00edculas y microbios y la contaminaci\u00f3n cruzada en el aire. Una sala blanca es un ambiente interior controlable creado para satisfacer un entorno de producci\u00f3n de alta limpieza, y su funcionamiento estable es una garant\u00eda importante para la producci\u00f3n limpia de las empresas farmac\u00e9uticas.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d5ce1fd elementor-widget elementor-widget-image\" data-id=\"d5ce1fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"533\" src=\"https:\/\/b3197424.assetcdn.net\/2.0\/3197424\/wp-content\/uploads\/2023\/08\/cleanroom-5-1-800x533.jpg?lossy=2&strip=1&webp=1\" class=\"attachment-medium size-medium wp-image-2239\" alt=\"C\u00f3mo deben mantenerse las salas blancas\" srcset=\"https:\/\/b3197424.assetcdn.net\/2.0\/3197424\/wp-content\/uploads\/2023\/08\/cleanroom-5-1-800x533.jpg?lossy=2&strip=1&webp=1 800w, https:\/\/b3197424.assetcdn.net\/2.0\/3197424\/wp-content\/uploads\/2023\/08\/cleanroom-5-1-1024x683.jpg?lossy=2&strip=1&webp=1 1024w, https:\/\/b3197424.assetcdn.net\/2.0\/3197424\/wp-content\/uploads\/2023\/08\/cleanroom-5-1-300x200.jpg?lossy=2&strip=1&webp=1 300w, https:\/\/b3197424.assetcdn.net\/2.0\/3197424\/wp-content\/uploads\/2023\/08\/cleanroom-5-1-768x512.jpg?lossy=2&strip=1&webp=1 768w, https:\/\/b3197424.assetcdn.net\/2.0\/3197424\/wp-content\/uploads\/2023\/08\/cleanroom-5-1-1536x1024.jpg?lossy=2&strip=1&webp=1 1536w, https:\/\/b3197424.assetcdn.net\/2.0\/3197424\/wp-content\/uploads\/2023\/08\/cleanroom-5-1.jpg?size=512x341&lossy=2&strip=1&webp=1 512w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a677181 elementor-widget elementor-widget-text-editor\" data-id=\"a677181\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>De acuerdo con la industria, un dise\u00f1o correcto y razonable es la premisa para garantizar el funcionamiento estable del <a href=\"https:\/\/www.maryatech.com\/es\/sistema-de-sala-blanca\/\">sala blanca<\/a>. Si no se presta atenci\u00f3n a la operaci\u00f3n y el mantenimiento o se realiza una operaci\u00f3n poco cient\u00edfica, la limpieza del aire de la sala limpia disminuir\u00e1 gradualmente, lo que provocar\u00e1 que muchos indicadores del entorno de producci\u00f3n real se desv\u00eden de los requisitos especificados, dando lugar a una disminuci\u00f3n de la calidad del producto o incluso a condiciones no cualificadas. \u00bfA qu\u00e9 aspectos hay que prestar atenci\u00f3n en el proceso de mantenimiento de una sala limpia?<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-528917c elementor-widget elementor-widget-text-editor\" data-id=\"528917c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>En primer lugar, la contaminaci\u00f3n del personal es la principal fuente de contaminaci\u00f3n. Las actividades del personal en el ambiente limpio aumentar\u00e1n obviamente el grado de contaminaci\u00f3n del ambiente limpio. Por lo tanto, las empresas deben formular las responsabilidades del personal de gesti\u00f3n a tiempo completo, el sistema de acceso para el personal de la sala limpia, la normativa sobre formaci\u00f3n y educaci\u00f3n del personal y la gesti\u00f3n de los \u201cprocedimientos de limpieza de personas\u201d para el personal que entra en la sala limpia.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0b3360a elementor-widget elementor-widget-text-editor\" data-id=\"0b3360a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>En segundo lugar, los equipos de la sala limpia, como suelos, paredes, techos, etc., difunden part\u00edculas. Por lo tanto, cuando los materiales y diversos equipos entran en la sala limpia, y el mantenimiento y la gesti\u00f3n de los equipos y tuber\u00edas relacionados, se debe garantizar que las part\u00edculas y los microorganismos no entren en la sala. Al mismo tiempo, las empresas deben formular m\u00e9todos de limpieza y esterilizaci\u00f3n de los diversos equipos e instalaciones de la sala limpia para prevenir y eliminar la generaci\u00f3n, retenci\u00f3n y reproducci\u00f3n de part\u00edculas de polvo y microorganismos en la sala limpia.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7801df7 elementor-widget elementor-widget-text-editor\" data-id=\"7801df7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>En tercer lugar, el personal debe llevar ropa limpia al entrar en la sala limpia, y hay que prestar atenci\u00f3n al material, el uso, la limpieza y otras cuestiones de la ropa. Las empresas deben hacer un buen trabajo en la gesti\u00f3n de la ropa limpia, incluyendo la adquisici\u00f3n y producci\u00f3n de ropa limpia, la gesti\u00f3n del uso de ropa limpia y las normas de limpieza de la ropa limpia.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d6b4945 elementor-widget elementor-widget-text-editor\" data-id=\"d6b4945\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>En cuarto lugar, el funcionamiento seguro de diversos equipos e instalaciones es la premisa para garantizar la seguridad de las salas blancas. Deben formularse los procedimientos operativos correspondientes para que diversos equipos e instalaciones funcionen con normalidad seg\u00fan las necesidades, incluidos los sistemas de aire acondicionado de purificaci\u00f3n, diversos sistemas de agua y electricidad, equipos e instalaciones de procesos de producci\u00f3n, etc. Con el fin de garantizar los requisitos del proceso de producci\u00f3n del producto y el nivel de limpieza del aire.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a9b8e2c elementor-widget elementor-widget-text-editor\" data-id=\"a9b8e2c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Por ejemplo, a una hora y en un lugar determinados, utilizando un contador de part\u00edculas para medir el n\u00famero de part\u00edculas de tama\u00f1o controlado; a una hora y en un lugar determinados, midiendo el n\u00famero de colonias asentadas o bacterias planct\u00f3nicas, etc.; en cuanto a la temperatura y la humedad, midiendo y comprobando el registro de medici\u00f3n continua. Adem\u00e1s, medir la diferencia de presi\u00f3n del filtro del sistema de aire acondicionado de purificaci\u00f3n, comprobar si el filtro de aire est\u00e1 bloqueado, si la junta instalada est\u00e1 en buen estado, si el filtro est\u00e1 da\u00f1ado o no, y comprobar el volumen de aire del dispositivo de escape local con un anem\u00f3metro, utilizando un son\u00f3metro para medir los niveles de ruido en un momento y lugar especificados.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1faadb0 elementor-widget elementor-widget-text-editor\" data-id=\"1faadb0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>En resumen, las empresas farmac\u00e9uticas deben controlar estrictamente la limpieza de la sala blanca en t\u00e9rminos de personal, equipos, instalaciones, gesti\u00f3n razonable y mantenimiento e inspecciones regulares. Garantizar la limpieza del entorno de producci\u00f3n de medicamentos de las empresas farmac\u00e9uticas es un factor importante para garantizar la producci\u00f3n segura y de calidad de los medicamentos. Adem\u00e1s de elegir una sala limpia y un sistema de sala limpia con un dise\u00f1o razonable, las empresas tambi\u00e9n necesitan llevar a cabo un mantenimiento y una gesti\u00f3n correctos y razonables de la sala limpia para garantizar una producci\u00f3n segura y de calidad. Las empresas farmac\u00e9uticas necesitan mejorar continuamente los equipos e instalaciones de la sala blanca y el sistema de aislamiento de los equipos para evitar la contaminaci\u00f3n cruzada causada por los propios equipos, a fin de sentar una base s\u00f3lida para la mejora de la calidad farmac\u00e9utica.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-746f25b e-flex e-con-boxed e-con e-parent\" data-id=\"746f25b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>How should clean rooms be maintained to avoid a decrease in air cleanliness? During the production process of medicines, it is necessary to prevent particulate and microbial contamination and cross-contamination in the air. A cleanroom is a controllable indoor environment created to meet a high-cleanliness production environment, and its stable operation is an important guarantee [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2239,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_templately_pack_id":"","_templately_imported_at":"","_templately_source":"","_templately_import_session_id":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[1,103],"tags":[],"class_list":["post-66218","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-all","category-industry-information"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>How should clean rooms be maintained? - Shanghai Marya<\/title>\n<meta name=\"description\" content=\"How should clean rooms be maintained to avoid a decrease in air cleanliness? 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